Dr. Stephen B. KennedyTest Vaccines Produce Year-Long Immune Response in Most Study ParticipantsResults from PREVAIL I—a large Ebola vaccine study that enrolled more than a thousand Liberians at Redemption Hospital in Monrovia during the first few months of 2015— have been published in the October 12th issue of The New England Journal of Medicine. The results show that the two test vaccines, cAd3-EBOZ and rVSV-ZEBOV, pose no major safety concerns and can produce immune responses within one month after vaccination that last for at least one year.The study was the first to be conducted by the Partnership for Research on Ebola Virus in Liberia, or PREVAIL. PREVAIL operates under the umbrella of a Joint Liberia-U.S. Clinical Research Partnership established in 2014 to assist Liberia develop vaccines and therapeutics to tackle Ebola.From February 2 through April 30, 2015, PREVAIL enrolled 1,500 men and women ages 18 and older in the study. Enrollees had no reported history of Ebola virus disease. The participants were divided at random into three groups of 500 each. One group received one test vaccine, the second group the other test vaccine, and the third group received a placebo (saltwater injection). It was important to include the placebo so that the research team could, compare how well the test vaccines worked.Participants gave blood samples before vaccination and again at one week, one month, six months, and one year post-vaccination. The study team tested each of these samples for infection-fighting antibodies against the Ebola virus. After one week, only modest levels of antibodies were seen with both vaccines. However, by one month, 71 percent of cAd3-EBOZ recipients and 84 percent of rVSV-ZEBOV recipients developed an antibody response compared with three percent of placebo recipients. At one year, the antibody responses were largely maintained in both groups: 64 percent of cAd3-EBOZ recipients and 80 percent of rVSV-ZEBOV recipients had antibody response compared with seven percent of placebo recipients.Some participants who received the test vaccines had temporary mild to moderate side effects, including headaches, muscle pain, fever and fatigue. Overall, no major safety concerns related to the vaccines were identified.“We were extremely thankful to have enrolled more than a thousand Liberian volunteers into the trial so quickly and to have more than 98 percent of those who enrolled return for their follow-up visits during the year,” says Dr. Stephen B. Kennedy, senior research scientist at the UL-PIRE Africa Center, an infectious disease research center based at the University of Liberia, and Co-Principal Investigator of the study. “The study was a true collaboration with the people of Liberia who participated and made it a success. To each and every one of them, we extend our deep gratitude.”PREVAIL conducts collaborative biomedical research in accordance with best practices, to advance science, strengthen health policy and practice, and improve the health of Liberians and people worldwide.“We cannot succeed in the fight against Ebola unless we identify primary prevention tools. Through PREVAIL, we are developing vaccines and therapeutics in our region that can help Liberians and the rest of the world,“ said Tolbert Nyenswah, Director General of the National Public Health Institute of Liberia (NPHIL) and Chairman of the Executive Committee of PREVAIL.The PREVAIL I study will continue to follow for several years those who had enrolled into the study to determine the long term benefits of the vaccines. The co-leaders of the study are Dr. Kennedy; Fatorma Bolay, PhD, Director, Division of Biomedical and Public Health Research at NPHIL; and Dr. H. Clifford Lane, Deputy Director for Clinical Research and Special Projects at the National Institute of Allergy and Infectious Diseases (NIAID), part of the US National Institutes of Health (NIH), which sponsored the study in collaboration with the Liberian Ministry of Health (MoH).“By developing research capacity and infrastructure to answer questions about Ebola and other infectious disease that are threats to global health, PREVAIL has become a successful model for the implementation of clinical trials during health outbreaks in resource-constrained environments,” noted Dr. Kennedy.The cAd3-EBOZ vaccine candidate was co-developed by NIAID’s Vaccine Research Center and GlaxoSmithKline (GSK), while rVSV-ZEBOV, initially engineered by scientists from the Public Health Agency of Canada, is now licensed to Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., (Merck). GSK and Merck provided the test vaccines for the study, according to a release yesterday. Reference: SB Kennedy et al. Phase 2 placebo-controlled trial of 2 vaccines to prevent Ebola in Liberia. New England Journal of Medicine 10.1056/NEJMoa1614067 (2017).Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)
WORCESTER, MA — Becker College recognized graduates during the College’s 230th Commencement Ceremony on May 5, 2018.Jocelyn Cornish, of Wilmington, graduated Magna Cum Laude with a Bachelor of Science degree in Nursing.Roy Trivellin III, of Wilmington, graduated Cum Laude with a Bachelor of Science degree in Nursing.About Becker CollegeFounded in 1784, Becker College is an undergraduate and graduate, career-focused private college, providing a supportive and inclusive learning community that prepares graduates for their first to last careers. Nearly 1,800 students from the United States and around the world live and learn on the College’s Worcester and Leicester campuses. With nationally recognized programs in nursing, game design and animal studies, Becker has been consistently ranked as a “Best College” for undergraduate education by The Princeton Review.(NOTE: The above announcement is from Becker College via Merit.)Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email email@example.com.Share this:TwitterFacebookLike this:Like Loading… RelatedSTUDENT SPOTLIGHT: Wilmington’s Mason & Ravagni Graduate From Becker CollegeIn “Education”STUDENT SPOTLIGHT: Wilmington’s Mason & Ravagni Named To Dean’s List At Becker CollegeIn “Education”STUDENT SPOTLIGHT: 4 Wilmington Students Graduate From Endicott CollegeIn “Education”
Sci-Tech Internet Over 2 million people signed up for the Facebook event. David Becker/Getty Images In July a tongue-in-cheek Facebook event was created to coordinate a raid on Area 51, the classified military base in Lincoln County, Nevada. It became an online sensation. Over 2 million Facebook users signed up, Jimmy Kimmel and Stephen Colbert gave it a spot on their respective talk shows, and the US Air Force strongly advised citizens against raiding the facility. But now, the Facebook event page has been taken down.It appears as though Facebook took the page down on Aug. 3 for violating community standards. Mathew Roberts, the event creator, posted a screenshot on his personal Facebook page of the notice Facebook had sent him saying it had taken down the event because it “went against” Facebook’s “Community Standards.””I never got any reason behind the event being removed,” Roberts told CNET. “I created a sister event which amassed about 15,000 people before being taken down for no reason.”After starting the Facebook event as a joke, Roberts is now planning an actual Area 51 festival in Nevada to take place Sept. 20, the day the facetious raid was to go down. He says he created another Facebook event, this time for the real festival that would take place somewhere that’s not a highly-classified military base, but this too was taken down by the social network. “I think it’s pretty reckless of Facebook, especially because I’m trying to direct people away from storming the base,” Roberts said. “And now I’ve lost my entire audience.” Roberts expects around 20,000 people to attend the festival. Facebook has been contacted for comment.The now-deleted Facebook event came with a brief description: “We will all meet up at the Area 51 Alien Center tourist attraction and coordinate our entry,” it read. “If we Naruto run, we can move faster than their bullets. Let’s see them aliens.””Naruto run” refers to the main character in the eponymous Naruto anime.The Facebook event created the Area 51 meme, which became a fixture on Twitter and Reddit throughout July. You can see some of our favourites below. Area 51 is a highly classified zone around 150 miles from Las Vegas, Nevada, a detachment of the famed Edwards Air Force Base. No one really knows what the base is used for, but it’s speculated to be a location for aircraft development, and as such Area 51 has become synonymous with alien conspiracies. The most popular involve alien spaceships or aliens themselves, all allegedly kept within the classified zone.The location reportedly received its name when, in 1951, the remains of the alleged Roswell UFO (said to have crashed in 1947) were brought to the base. In 2013, the CIA issued a 355-page declassified report detailing the birth of Area 51 and the U-2 spy planes developed and tested there.Originally published Aug. 5, 7:30 p.m. PT. Update, 9:38 p.m.: Adds comment from event creator Mathew Roberts. Facebook Comments 7 #Area51 let’s see them aliens pic.twitter.com/0zmL8dFdoy— Ash (@taintdchinadoll) July 12, 2019 Share your voice The greatest alien encounter movies, ranked 41 Photos My motivation to study Vs. My motivation to get into Area 51 pic.twitter.com/lF7TbFb5RU— College Student (@FactsOfSchool) July 13, 2019 Tags Enlarge Image Reddit/AnonEnigma
The Bombay Stock Exchange in Mumbai on Feb 29, 2016 (representational image).IANSShares of Ramco Systems rose as high as 7.6 percent on Tuesday after the Chennai-based enterprise software company informed stock exchanges that air medical service Air Evac SMS Inc. has completed implementation of its aviation software Ramco Aviation V5.7 across its 135 bases in the US. The stock later gave up gains partially to trade at Rs 355 at around 1 pm.Read: Ramco Systems, Jubilant Life shares jump on deal winsAir Evac’s fleet comprises 150 helicopters with about 700 active users and is a subsidiary of Air Medical Group Holdings with which Ramco Systems has a decade-long business relationship.”The implementation of Ramco Aviation suite covers Line, Hangar & Shop Maintenance, Engineering Change Management, Technical Records, Inventory Management, Procurement Management, and Facility Management along with Advance Reporting tools,” Ramco Systems said in a regulatory filing to the Bombay Stock Exchange (BSE).For the quarter ended December 31, 2016, Ramco Systems had reported net profit of Rs 3 crore on total sales of Rs 113 crore.The BSE Sensex was trading in the red at 28,625.
U.S. President Donald Trump looks down while speaking to reporters about healthcare during an energy policy discussion with leaders of American Indian tribes and U.S. governors at the White House in Washington, U.S., June 28, 2017. REUTERSUS president Donald Trump urged Republican senators in a tweet on Friday to repeal Obamacare immediately if they cannot agree on a new plan to replace it, muddying the waters as congressional leaders struggle for consensus on healthcare legislation.Senate Republican leaders had set Friday as the target for rewriting legislation for a simultaneous repeal and replacement of extensive parts of the 2010 Affordable Care Act, the law dubbed Obamacare that expanded health insurance coverage to 20 million people.The deadline seemed unlikely to be met given that most senators had left Washington ahead of next week’s recess, without agreement on a clear direction for the healthcare bill, and Trump’s tweet did not appear to gain political traction.Financial markets showed little reaction to Trump’s suggestion, with the benchmark S&P 500 index edging about 0.15 percent higher on the day. Shares of most health insurers gained fractionally while hospital stocks were little changed.Trump wrote on Twitter Friday morning, “If Republican Senators are unable to pass what they are working on now, they should immediately REPEAL, and then REPLACE at a later date!”The White House said later that Trump was still “fully committed” to pushing the Republican draft healthcare bill through the Senate, although it was looking at every option for repealing and replacing Obamacare.“The president hasn’t changed his thinking at all,” White House spokeswoman Sarah Sanders told reporters.The current Senate legislation would repeal parts of Obamacare, roll back its expansion of the Medicaid government healthcare program for the poor, eliminate most of Obamacare’s taxes and replace Obamacare insurance subsidies with a system of tax credits to help individuals buy private health insurance.Conservative and moderate Republicans have spent recent days pushing and pulling the bill in opposite directions as Senate Majority leader Mitch McConnell sought common ground. Moderates want more equity for low-income Americans, while conservatives are fighting to loosen insurance regulations.Shortly before his January inauguration, Trump urged lawmakers to repeal and replace Obamacare at the same time. Congressional Republicans had considered earlier this year first repealing, then replacing Obamacare, but backed away after some lawmakers protested that that approach could create a gap in insurance coverage for millions.On Friday, Republican senator Ben Sasse who had suggested that Congress first repeal Obamacare and then replace it, tweeted: “Glad you agree, Mr. Pres.” Conservative Senator Rand Paul also backed the idea.But others on Capitol Hill sounded annoyed. A senior Senate Republican aide, speaking on condition of anonymity, said that if lawmakers had been able to get the votes for repealing Obamacare first, then replacing it, “senators would have done that in January. It doesn’t have the votes, and it’s a waste of valuable time to discuss it.”Annie Clark, a spokeswoman for moderate Republican Senator Susan Collins, said the lawmaker would not support the strategy. McConnell’s spokesman declined to comment on Trump’s tweet.A senior House of Representatives Republican, Ways and Means Committee Chairman Kevin Brady, said in an interview for CSPAN’s “Newsmakers” program that lawmakers’ goal should continue to be “not simply repealing but to start to put into place the elements that can make healthcare affordable.”
A group of Rohingya refugee people walk in the water after crossing the Bangladesh-Myanmar border in Teknaf. ReutersA number of US interfaith leaders on Wednesday called upon the international community to impose full sanctions on Myanmar until it stops what they said the textbook case of genocide against Rohingyas and restore citizenship of its displaced Muslim minority, reports UNB.They also called upon the world leaders to stand in solidarity with Rohingyas and invoke the convention for the prevention and punishment of genocide to protect the Rohingyas from persecution.At a press conference held at a city hotel after their recent visit to Rohingya camps in Cox’s Bazar, the American Buddhist, Jewish, Christian and Muslim community leaders praised Bangladesh’s humanitarian assistance and provision of security to the Rohingyas.They also endorsed prime minister Sheikh Hasina’s call that Rohingyas restored in their land in Myanmar with clear mandate for the UN to defend Rohingyas and bring the perpetrators of these crime to justice.Noor Ankis, 25, whose husband Ayub, a leader of the unregistered makeshift camp in Kutupalong, was killed late last month, poses for a picture with her two children in Cox’s Bazar. ReutersA 14-member delegation of American interfaith leaders, including that of two Buddhists, two Jews, two Muslim Imams and several Christians, earlier visited the Rohingya camps and listened to Rohingya voices. The visit was arranged by ‘Interfaith Coalition to Stop Genocide in Burma’.Upon getting back to the USA, they said, they will amplify Rohingya voices in the US Congress, administration and the civil society to mobilise public opinion across the globe to resolve the crisis and ensure safe return of Rohingyas to their mother land with security, dignity, rights and citizenship.Speaking at the press conference, a leading Buddhist American scholar Alan Senauke said what he saw at Balukhali Rohingya camp and heard the stories of the persecuted people make his heart weep. “Violence that directed against children, women, men and the families is the worst form of cruelty. To my understanding, the murder and displacement of Rohingyas in Myanmar has nothing to do with the Buddha’s teaching.”He also called upon the Buddhists around the world to stand with Rohingyas’ cry for safety, justice and citizenship. “We’re greatly disturbed by what many see as slander and distortion of the Buddha’s teaching.”Alan Senauke also said the hatred, systematic persecution and ethnic cleansing of Rohingyas stand in stark contradiction to monastic precepts and Buddha’s teaching on universal morality, peace and tolerance.He said they will raise fund in the USA to drum up support from Buddhists to stand by Rohingyas and raise voice for ensuring their security, justice and citizenship.Rabbi David Saperstein, a Jewish leader and immediate past US Ambassador at Large for religious freedom, said religious persecution was central component of the increasingly harsh oppression of the Rohingyas over the past decades.”We’ve heard the stories of mothers, fathers, brothers and sisters of watching how their family members were killed in front of them, and how they faced persecution,” he said.The Jewish leader said they will try to encourage the American authorities and international community to take the right step so that they Rohingyas can return to their country with protection and rights, including religious freedom.
Congress on Wednesday hit back at the government for targeting it for disruptions in the Indian Parliament alleging that the National Democratic Alliance (NDA) dispensation was being “very insensitive” to the demands of its detractors and pursuing the agenda of “opposition-mukt bharat.” Leader of the Opposition in the Upper House of Parliament Rajya Sabha, Ghulam Nabi Azad also singled out Parliamentary Affairs Minister M Venkaiah Naidu for attack remarking that “I have never seen a Parliamentary Affairs Minister spearheading confrontation.” Also Read – Punjab on alert after release of excess water from Bhakra damAsking the government to shed its “arrogance and vendetta politics”, Azad, who had been Parliamentary Affairs Minister thrice, said when in power, Congress often took up issues raised by the Opposition.“Then, I had told my colleagues that duty of Parliamentary Affairs Minister is to work with all parties. From Treasury benches, I had said that Parliamentary Affairs Minister represents both government and opposition,” Azad said targeting Naidu.Insisting that the government’s efforts to take the opposition along was a failure, he recalled that in 1991-96, Congress ran a minority government but still introduced revolutionary changes in the economy. “Congress had the ability to take Opposition along.”
Kolkata: Some people set the grass on fire on a vacant plot belonging to the Housing Infrastructure Development Corporation ( HIDCO) in New Town.Two fire tenders fought the blaze for two hours before brining it under control. No one was injured in the incident. Senior Housing Infrastructure Development Corporation officials said some people might have set the grass on fire to prepare fodder. People saw smoke coming out of the vacant plot situated close to the Mother’s Wax Museum near Pancha More around 10.30 am. Also Read – Rs 13,000 crore investment to provide 2 lakh jobs: MamataDue to the thick smoke the visibility dropped and cars coming towards Kolkata were diverted as the divers could not see anything. The smoke which was carried by wind affected people,particularly the elderly ones, who complained of breathing difficulty and burning sensation in the eyes. Local people informed the police and fire brigade. The police cordoned off the area to facilitate fire fighters to put out the flame. Local people alleged that some people staying in the nearby villages often set the grass on vacant land on fire. However, they could not be caught as they leave the area after setting the grass on fire. On earlier occasions, the quantum of fire was not so intense but the intensity of the fire that broke on Thursday was so high that it affected the residents of nearby buildings badly. They demanded action against the habitual offenders.